Paper: | ITT-P4.11 | ||
Session: | Biomedical and biometric applications | ||
Time: | Friday, May 21, 15:30 - 17:30 | ||
Presentation: | Poster | ||
Topic: | Industry Technology Track: Biomedical | ||
Title: | TECHNIQUES FOR DETECTING APPROXIMATE TANDEM REPEATS IN DNA | ||
Authors: | Thao Tran; Georgia Institute of Technology | ||
Vincent Emanuele II; Georgia Institute of Technology | |||
G. Tong Zhou; Georgia Institute of Technology | |||
Abstract: | The detection of tandem repeats is important in biology and medicine as it can be used for phylogenic studies and disease diagnosis. This paper proposes two techniques for detecting approximate tandem repeats (ATRs) in DNA sequences. First, an evolutionary force heuristic is proposed to merge interspersed perfect tandem repeat sequences into an ATR structure. Next, a more general method is presented using a product spectrum of Fourier nucleotide subsequences to detect hidden periodicity. The Fourier method is sensitive to ATRs and is robust in the presence of substitutions, insertions, and deletions. | ||
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